Natural-language process brief
Start with penicillin, cultured meat, antibodies, fermentation, vaccines, plasmids, cell therapy, water, or emissions. Acatian maps the brief to a process architecture.
Product
Bioprocess engineering software for plant-wide decisions.
Build, simulate and review one governed model across process development, scale-up, manufacturing, economics and environmental assessment.What is Acatian?
A shared engineering model of the process and the plant around it.
Acatian connects flowsheets, mass and energy balances, dynamic models, equipment, scheduling, TEA, LCA, data provenance and technical review. A change to the process remains traceable across the calculations and outputs it affects.
Production trains, utilities, cleaning, logistics and operating constraints remain part of one engineering model.
Edit equipment, streams, utilities, cleaning loops and operating assumptions in one workspace.
Capabilities
One model from definition to engineering decision.
Build the process architecture first. Add physics, data, economics and review evidence without creating disconnected copies of the model.Flowsheet + equipment builder
Drag equipment, connect animated streams, add CIP/SIP, recycle, heat reuse, utilities, valves, sensors, QC nodes, and support infrastructure.
Models, equations, and downloads
Work with mass and energy balances, chemical equations, stream tables, parameters, economics, standards, LCA inventories, TEA cost drivers, and downloadable CSV/SVG datasets.
AI-assisted engineering
Ask what blocks oxygen transfer, ammonium control, media cost, scale-up, cleaning, heat recovery, or facility readiness, then jump to the right tool module.
Process models
Begin with an industrial route, then make it yours.
Each starting model includes the main process, support systems, cleaning, utilities, operating mode and the inputs still needed for a defensible result.10,000 L mAb fed-batch model
Generates seed train, production STR, harvest, depth filtration, Protein A, low-pH viral inactivation, polishing, UF/DF, fill, QC release, CIP/SIP, mass balance, LCA inventory, and TEA cost stack.
Cultured meat perfusion plant
Shows media preparation, seed expansion, perfusion bioreactor, cell-retention, harvest wash, formulation, packaging, ammonia and lactate boundaries, heat reuse, wastewater, and water-reuse loops.
Penicillin fermentation route
Builds sterile media, aerobic fermentation, cell removal, extraction, solvent recycle, crystallization, drying, emissions, hazardous solvent checks, route scheduling, and downstream yield sensitivity.
Benefits
Reduce the handoffs that make scale-up decisions slow and fragile.
Acatian is designed for engineering teams that need more than a drawing, a single calculation or another disconnected spreadsheet.One controlled model
Equipment, streams, equations, schedules, costs, impacts, sources and model maturity remain linked to the same project version.
Faster scenario decisions
Compare process modes, scales, equipment trains, campaigns and uncertain assumptions without rebuilding the analysis in separate files.
Clear technical limits
Every output states its evidence class, missing inputs, validity boundary and the work required before the result is decision-ready.
Reusable engineering knowledge
Carry reviewed templates, parameters and calculation methods forward while keeping customer and project data private and attributable.
Extensions
Connect established engineering work to a modern system.
Versioning, APIs, company data, dynamic models and uncertainty analysis extend the core flowsheet without hiding the calculation basis.Keep existing simulator work
Import or reconstruct one representative process, validate mass balance and economics, then evaluate scenarios collaboratively in the browser.
Versions, branches, comments
Shared projects, roles, invitations, audit history, model versions, process alternatives, and comparison-ready decision records.
REST, Python, webhooks
JSON process model, API handoffs, cloud batch runs, parameter sweeps, Monte Carlo cases, and LIMS/historian/ERP connectors.
Dynamic plant intelligence
Time-dependent cell growth, metabolites, live plant data, calibration, soft sensors, anomaly checks, and online prediction roadmap.
Native risk analysis
Sensitivity, Sobol-style ranking, probabilistic costs, uncertainty bands, parameter fitting, and scenario comparison without spreadsheet add-ins.
Transparent COGS + CAPEX
Regional cost indices, vendor quotes, CAPEX ranges, media and consumables, NPV/IRR/break-even, cash runway, and key cost drivers.
Who uses Acatian?
Organized around the decisions each engineering team owns.
Choose the role closest to your work, then follow the linked workflow and required evidence.Reconcile source and receiving-site models, equipment, controls, batch data and validation evidence.
Process developmentScale-up and process characterizationConnect experiments, kinetics, operating modes, boundaries and uncertainty to the full process route.
ManufacturingCapacity and campaign planningSchedule reusable equipment, rooms, labor, utilities, cleaning, maintenance, QC and material availability.
TEA + LCACost and environmental decisionsUse the same material, energy, yield and scheduling basis for cost intervals and life-cycle inventory.
CDMO + engineeringCustomer intake and facility fitEvaluate process variants, delivery risk, equipment occupancy and transparent commercial assumptions.
Technical reviewValidation and reproducibilityInspect assumptions, numerical checks, sources, branches, versions, gaps and approval context.
High-demand biopharma example
Therapeutic monoclonal antibody production, built as a guided product demo.
Acatian uses an original CHO monoclonal-antibody platform process as the front-page walkthrough because it touches the full problem: upstream cell culture, downstream purification, viral safety, scheduling, economics, LCA, quality, and scale-up physics.
Example basis
Based on common CHO/mAb platform process structure and general bioprocess-engineering practice. Acatian is not copying proprietary simulator files; it demonstrates an original, editable workflow around this process type.
FAQ + resources